Tirofiban (Aggrastat®)

Tirofiban-induced coronary thrombolysis.

receptor antagonists during coronary angioplasty has become more widespread due to several trials demonstrating clinical benefit during and after the p r o c e d u r e . – 3 These agents act by blocking the GP IIb/IIIa receptor on the surface of the platelet. The GP IIb/IIIa receptor binds circulating adhesive macromolecules and cross-links with the receptors of surrounding platelets, resulting...

Tirofiban usage and prognosis after myocardial infarction

I read the article by Kaymaz et al. (1), entitled “The effects of tirofiban infusion on clinical and angiographic outcomes of patients with STEMI undergoing primary PCI.” which was recently published online in your journal, with great interest. In their study, the authors reported that additional tirofiban usage significantly improves myocardial reperfusion, ST-segment resolution, in-hospital m...

Subacute Myocardial Rupture Following Tirofiban Treatment

A 74-year-old male patient was admitted to our emergency department with post-MI angina. On account of the anginal complaint that continued for three days, a coronary artery angiography was undertaken. A percutaneous transluminal coronary angioplasty was performed, followed by the implantation of a coronary stent, and coronary perfusion (TIMI-3) was achieved in the left anterior descending arte...

Drug Eluting Stents; A new era in Interventional Cardiology

INTRODUCTION Over the last decade or so, no other subspecialty of medicine has seen such technological innovations, as interventional cardiology. These advances have revolutionized the management of coronary artery disease. From statin drugs to oral platelets inhibitors like clopidogrel and ticlopidine, intravenous platelet glycoprotein IIb/IIIa receptor blockers like Abciximab (Reo-Pro), Eptif...

Tirofiban and Clopidogrel before Saphenous Vein Stenting